How to detect antibody denaturation and aggregation in biotechnology applications? (VIDEO)
Date: - Categories: Applications & Technologies
Study of the antibody thermal stability
Assessing the thermal stability of antibodies is essential to ensure their effectiveness, as heat exposure can induce denaturation or aggregation during production, storage or use.
These irreversible changes impact their structure and performance, making their control critical for optimizing formulations and ensuring biopharmaceutical quality. Microcalorimetry enables precise measurement of these transitions, including the denaturation and aggregation of antibodies such as Immunoglobulin G (IgG).
From lab to life : the experiment explained
Watch a video presenting a case study on how to detect denaturation and aggregation of an antibody like Immunoglobulin G.
Our Microcalvet ULTRA microcalorimeter : the perfect fit for studies on thermal stability or drug delivery systems
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High sensitivity with 3D sensors
Necessary to detect thermal event on diluted protein solutions.
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Removable cells
For easy cleaning (particularly significant with proteins that aggregate regularly).
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Modifiable temperature conditions
For increased flexibility and replication of real life conditions.
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External coupling capacity
Designed to increase your research options including manometry, BET instrumentation, gas analyzers, humidity controllers and gas panels.
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If you want more information or if you need a quote, contact us.
